Hypothalamic neurons from a developmental aspect.

Developmental changes in embryonic hypothalamic neurons during prenatal fat exposure.

Maternal consumption of a fat-rich diet during pregnancy, which causes later overeating and weight gain in offspring, has been shown to stimulate neurogenesis and increase hypothalamic expression of orexigenic neuropeptides in these postnatal offspring. The studies here, using an in vitro model that mimics in vivo characteristics after prenatal high-fat diet (HFD) exposure, investigate whether ...

Plasma seed priming in green cumin, physiological and developmental aspect

Green cumin is an herbaceous, annual, delicate, and aromatic plant in the family Apiaceae, also known with other names such as " kammun " and "senut", which is among the oldest and most economical as well as the second most popular medicinal plants after black pepper. In this study, pretreatment of cumin seed was studied with plasma technology without using chemicals through damage to seed for ...

Differentiation of hypothalamic-like neurons from human pluripotent stem cells.

The hypothalamus is the central regulator of systemic energy homeostasis, and its dysfunction can result in extreme body weight alterations. Insights into the complex cellular physiology of this region are critical to the understanding of obesity pathogenesis; however, human hypothalamic cells are largely inaccessible for direct study. Here, we developed a protocol for efficient generation of h...

Role of developmental factors in hypothalamic function

The hypothalamus is a brain region which regulates homeostasis by mediating endocrine, autonomic and behavioral functions. It is comprised of several nuclei containing distinct neuronal populations producing neuropeptides and neurotransmitters that regulate fundamental body functions including temperature and metabolic rate, thirst and hunger, sexual behavior and reproduction, circadian rhythm,...

Neuronal Hypothalamic Plasticity in Chicken: a Developmental and Pharmacological Perspective